218803

• Gene Symbol: Pde2a
• Gene Name: phosphodiesterase 2A, cGMP-stimulated
• Gene Aliases: CGS-PDE, cGSPDE
• Chromosome Location: Chr.7: 101421691 - 101512829 on Build GRCm38
• UniGene ID: Mm.247564
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Pde2a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001008548.4	NP_001008548.1	30, 31	2843
	NM_001143848.2	NP_001137320.1	30, 31	2855
	NM_001143849.2	NP_001137321.1	29, 30	2688
	NM_001243757.1	NP_001230686.1	30, 31	2750
	NM_001243758.1	NP_001230687.1	30, 31	2747
GenBank mRNA	AK158560.1	-	30, 31	2748
	AK158888.1	-	21, 22	1731
	AK159012.1	-	30, 31	2637
	AK170395.1	-	30, 31	2626
	AK170573.1	-	29, 30	2628
	AK172397.1	-	29, 30	2629
	BC006845.1	-	10, 11	901
	BC029810.1	-	14, 15	1345
	BC057029.1	-	31, 32	2749
	BC086800.1	-	30, 31	2825	30543765

More Information

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cAMP catabolic process
protein targeting to mitochondrion
signal transduction
metabolic process
positive regulation of gene expression
cAMP-mediated signaling
cGMP-mediated signaling
negative regulation of cAMP biosynthetic process
regulation of cGMP metabolic process
negative regulation of protein import into nucleus, translocation
cellular response to drug
cellular response to macrophage colony-stimulating factor stimulus
negative regulation of vascular permeability
positive regulation of vascular permeability
cGMP catabolic process
positive regulation of inflammatory response
establishment of endothelial barrier
cellular response to mechanical stimulus
cellular response to cGMP
cellular response to granulocyte macrophage colony-stimulating factor stimulus

Function(s)

nucleotide binding
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
phosphoric diester hydrolase activity
drug binding
hydrolase activity
cAMP binding
cGMP binding
TPR domain binding
GAF domain binding
protein homodimerization activity
metal ion binding