22664

• Gene Symbol: NEDD4L
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Gene Aliases: NEDD4-2, NEDD4.2, RSP5, hNEDD4-2
• Chromosome Location: Chr.18: 58044362 - 58401540 on Build GRCh38
• UniGene ID: Hs.185677
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NEDD4L
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001144964.1	NP_001138436.1	2	350
	NM_001144965.1	NP_001138437.1	2	302
	NM_001144967.2	NP_001138439.1	2	396
	NM_001144968.1	NP_001138440.1	2	292
	NM_001144969.1	NP_001138441.1	2	292
	NM_001243960.1	NP_001230889.1	2	396
	NM_015277.5	NP_056092.2	2	396
	XM_006722428.3	XP_006722491.1	2	412
	XM_017025678.1	XP_016881167.1	2	411
GenBank mRNA	AB071179.1	-	2	227
	AF385931.1	-	2	351
	AY112983.1	-	2	302
	AY112984.2	-	2	292
	AY112985.2	-	2	296
	AY256662.1	-	3	235
	AY312514.1	-	2	113
	BC032597.1	-	2	423	5528964
	DB473368.1	-	2	386

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
regulation of membrane depolarization
protein monoubiquitination
sodium ion transport
cellular sodium ion homeostasis
excretion
response to metal ion
protein ubiquitination
viral life cycle
water homeostasis
ion transmembrane transport
regulation of ion transmembrane transport
regulation of protein catabolic process
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
positive regulation of endocytosis
regulation of membrane repolarization
protein K48-linked ubiquitination
ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of sodium ion transmembrane transport
positive regulation of dendrite extension
negative regulation of protein localization to cell surface
negative regulation of sodium ion transmembrane transporter activity
positive regulation of caveolin-mediated endocytosis

Function(s)

ubiquitin-protein transferase activity
protein binding
potassium channel regulator activity
ligase activity
sodium channel regulator activity
potassium channel inhibitor activity
sodium channel inhibitor activity
ion channel binding