22855

• Gene Symbol: NEDD4L
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Gene Aliases: NEDD4-2, NEDD4.2, RSP5, hNEDD4-2
• Chromosome Location: Chr.18: 58044362 - 58401540 on Build GRCh38
• UniGene ID: Hs.185677
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NEDD4L
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001144964.1	NP_001138436.1	31	4217
	NM_001144965.1	NP_001138437.1	31	4169
	NM_001144966.2	NP_001138438.1	30	4094
	NM_001144967.2	NP_001138439.1	31	4263
	NM_001144968.1	NP_001138440.1	31	4159
	NM_001144969.1	NP_001138441.1	30	4099
	NM_001144970.2	NP_001138442.1	29	4142
	NM_001144971.1	NP_001138443.1	31	4187
	NM_001243960.1	NP_001230889.1	29	4071
	NM_015277.5	NP_056092.2	30	4203
	XM_005266658.4	XP_005266715.2	28	4194
	XM_005266660.4	XP_005266717.2	27	4138
	XM_005266663.4	XP_005266720.2	26	4078
	XM_006722421.3	XP_006722484.2	27	4133
	XM_006722424.3	XP_006722487.2	24	3686
	XM_006722425.3	XP_006722488.2	23	3630
	XM_006722426.3	XP_006722489.1	33	4411
	XM_006722428.3	XP_006722491.1	32	4333
	XM_006722430.3	XP_006722493.1	31	4241
	XM_011525887.2	XP_011524189.1	33	4391
	XM_017025676.1	XP_016881165.1	25	3883
	XM_017025677.1	XP_016881166.1	24	3827
	XM_017025678.1	XP_016881167.1	31	4272
	XM_017025679.1	XP_016881168.1	30	4187
	XM_017025680.1	XP_016881169.1	27	3875
	XM_017025681.1	XP_016881170.1	26	3677
GenBank mRNA	AB007899.1	-	29	4043
	AB071179.1	-	30	4035
	AF070601.1	-	1	788
	AK091189.1	-	3	1911

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
regulation of membrane depolarization
protein monoubiquitination
sodium ion transport
cellular sodium ion homeostasis
excretion
response to metal ion
protein ubiquitination
viral life cycle
water homeostasis
ion transmembrane transport
regulation of ion transmembrane transport
regulation of protein catabolic process
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
positive regulation of endocytosis
regulation of membrane repolarization
protein K48-linked ubiquitination
ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of sodium ion transmembrane transport
positive regulation of dendrite extension
negative regulation of protein localization to cell surface
negative regulation of sodium ion transmembrane transporter activity
positive regulation of caveolin-mediated endocytosis

Function(s)

ubiquitin-protein transferase activity
protein binding
potassium channel regulator activity
ligase activity
sodium channel regulator activity
potassium channel inhibitor activity
sodium channel inhibitor activity
ion channel binding