2332

• Gene Symbol: ABCA1
• Gene Name: ATP binding cassette subfamily A member 1
• Gene Aliases: ABC-1, ABC1, CERP, HDLDT1, TGD
• Chromosome Location: Chr.9: 104781002 - 104928246 on Build GRCh38
• UniGene ID: Hs.659274
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ABCA1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005502.3	NP_005493.2	4	605
	XM_005251773.2	XP_005251830.1	4	514
	XM_005251776.2	XP_005251833.1	3	354
	XM_011518339.2	XP_011516641.1	5	589
	XM_011518340.2	XP_011516642.1	6	804
	XM_011518341.2	XP_011516643.1	5	589
	XM_011518344.2	XP_011516646.1	5	589
	XM_017014378.1	XP_016869867.1	5	787
	XM_017014379.1	XP_016869868.1	5	1195
	XM_017014380.1	XP_016869869.1	5	521
	XM_017014381.1	XP_016869870.1	5	587
	XM_017014382.1	XP_016869871.1	3	1052
GenBank mRNA	AB037924.1	-	3	288
	AB055982.1	-	3	201
	AB445477.1	-	3	201
	AF165281.1	-	2	141
	AF258627.1	-	4	596
	AF285167.1	-	4	491
	AJ012376.1	-	2	141
	AK024328.1	-	4	514
	BC146856.1	-	4	415	9056784
	BX955241.1	-	4	605

More Information

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter, primary active transporter, transporter

Gene Ontology Categories:

Process(es)

peptide secretion
protein lipidation
phagocytosis, engulfment
lysosome organization
G-protein coupled receptor signaling pathway
response to nutrient
cholesterol metabolic process
negative regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
endosomal transport
positive regulation of cAMP biosynthetic process
intracellular cholesterol transport
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
high-density lipoprotein particle assembly
response to laminar fluid shear stress
apolipoprotein A-I-mediated signaling pathway
lipoprotein metabolic process
response to drug
cholesterol homeostasis
reverse cholesterol transport
phospholipid translocation
interleukin-1 beta secretion
phospholipid homeostasis
response to low-density lipoprotein particle
platelet dense granule organization
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to cholesterol
anion transmembrane transport

Function(s)

receptor binding
protein binding
ATP binding
phospholipid binding
phospholipid transporter activity
anion transmembrane transporter activity
cholesterol binding
cholesterol transporter activity
syntaxin binding
small GTPase binding
apolipoprotein binding
apolipoprotein A-I binding
apolipoprotein A-I receptor activity
ATPase activity, coupled to transmembrane movement of substances
ATPase binding