240549

• Gene Symbol: Myc
• Gene Name: myelocytomatosis oncogene
• Gene Aliases: AU016757, Myc2, Niard, Nird, bHLHe39
• Chromosome Location: Chr.15: 61985341 - 61990361 on Build GRCm38
• UniGene ID: Mm.2444
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Myc
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001177352.1	NP_001170823.1	2	712
	NM_001177353.1	NP_001170824.1	2	709
	NM_001177354.1	NP_001170825.1	2	709
	NM_010849.4	NP_034979.3	2	712
GenBank mRNA	AK087961.1	-	2	504
	AK133952.1	-	2	486
	AK145084.1	-	2	666
	BC006728.1	-	1	186
	BC138931.1	-	2	175	8861953
	BC138932.1	-	2	175	8861954
	X01023.1	-	2	692

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012603, BC091699, AY679729, AY679730.

Panther Classification:

Molecular Function -

basic helix-loop-helix transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
branching involved in ureteric bud morphogenesis
B cell apoptotic process
positive regulation of mesenchymal cell proliferation
regulation of oxidative phosphorylation
positive regulation of B cell apoptotic process
glucose metabolic process
chromatin remodeling
transcription, DNA-templated
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
pyruvate transport
amino acid transport
cellular iron ion homeostasis
activation of cysteine-type endopeptidase activity involved in apoptotic process
cellular response to DNA damage stimulus
inner mitochondrial membrane organization
cell cycle arrest
regulation of mitotic cell cycle
cell proliferation
positive regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage
response to radiation
response to gamma radiation
regulation of gene expression
negative regulation of gene expression
positive regulation of mitochondrial membrane potential
Wnt signaling pathway
protein processing
transformation of host cell by virus
negative regulation of protein binding
regulation of telomere maintenance
cellular response to drug
skeletal muscle cell differentiation
middle ear morphogenesis
regulation of apoptotic process
positive regulation of catalytic activity
response to alkaloid
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
pigmentation
canonical Wnt signaling pathway involved in positive regulation of wound healing
canonical Wnt signaling pathway involved in negative regulation of apoptotic process
canonical Wnt signaling pathway involved in positive regulation of apoptotic process
negative regulation of monocyte differentiation
positive regulation of cell cycle
positive regulation of glycolytic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of glucose import
lactic acid secretion
positive regulation of fibroblast proliferation
negative regulation of fibroblast proliferation
skeletal system morphogenesis
positive regulation of epithelial cell proliferation
detection of mechanical stimulus involved in sensory perception of sound
chromosome organization
negative regulation of cell division
canonical Wnt signaling pathway
negative regulation of cell death
positive regulation of metanephric cap mesenchymal cell proliferation
positive regulation of cellular respiration
positive regulation of DNA biosynthetic process
positive regulation of response to DNA damage stimulus
positive regulation of ATP biosynthetic process
positive regulation of apoptotic signaling pathway

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein complex binding
sequence-specific DNA binding
protein heterodimerization activity
protein dimerization activity
repressing transcription factor binding
E-box binding