24674

• Gene Symbol: NOX4
• Gene Name: NADPH oxidase 4
• Gene Aliases: KOX, KOX-1, RENOX
• Chromosome Location: Chr.11: 89324353 - 89589611 on Build GRCh38
• UniGene ID: Hs.371036
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOX4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001143836.2	NP_001137308.1	2	445
	NM_001143837.1	NP_001137309.1	5	590
	NM_001291926.1	NP_001278855.1	2	445
	NM_001291927.1	NP_001278856.1	2	195
	NM_001300995.1	NP_001287924.1	2	168
	NM_016931.4	NP_058627.1	2	445
	NR_120406.1		2	445
	XM_006718849.3	XP_006718912.1	2	373
	XM_011542857.2	XP_011541159.1	2	245
	XM_017017841.1	XP_016873330.1	2	373
	XM_017017843.1	XP_016873332.1	2	373
	XM_017017844.1	XP_016873333.1	2	337
GenBank mRNA	AB041035.1	-	2	365
	AF254621.1	-	2	212
	AF261943.1	-	2	126
	AJ704725.1	-	2	126
	AJ704726.1	-	2	126
	AJ704727.1	-	2	126
	AJ704728.1	-	2	126
	AJ704729.1	-	2	126
	AK057189.1	-	5	590
	AK291830.1	-	2	208
	AK298323.1	-	2	139
	AK298328.1	-	2	195
	AK298376.1	-	2	208
	AK311389.1	-	2	173
	AY288918.1	-	2	126
	BC040105.1	-	2	198	5590269
	BC051371.1	-	2	445
	DA970477.1	-	5	590

More Information

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
cell morphogenesis
response to hypoxia
superoxide metabolic process
inflammatory response
cell aging
negative regulation of cell proliferation
gene expression
positive regulation of smooth muscle cell migration
superoxide anion generation
positive regulation of apoptotic process
positive regulation of MAP kinase activity
bone resorption
homocysteine metabolic process
positive regulation of stress fiber assembly
positive regulation of protein kinase B signaling
cardiac muscle cell differentiation
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to cAMP
cellular response to glucose stimulus
cellular response to gamma radiation
cellular response to transforming growth factor beta stimulus
reactive oxygen species metabolic process
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process

Function(s)

nucleotide binding
protein binding
electron carrier activity
NAD(P)H oxidase activity
superoxide-generating NADPH oxidase activity
oxygen sensor activity
heme binding
flavin adenine dinucleotide binding
modified amino acid binding