251284

Gene Symbol:

NR1D1 THRA

Gene Name:

nuclear receptor subfamily 1 group D member 1

thyroid hormone receptor, alpha

Gene Aliases:

EAR1, THRA1, THRAL, ear-1, hRev

AR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, c-ERBA-1

Chromosome Location:

Chr.17: 40092784 - 40100725 on Build GRCh38

Chromosome Location:

Chr.17: 40062193 - 40093867 on Build GRCh38

UniGene ID:

Hs.592130

Hs.724

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: NR1D1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_021724.4	NP_068370.1	7	2081
GenBank mRNA	AK300155.1	-	4	777
	AK315270.1	-	8	1823
	AY429554.1	-	4	406
	BC047875.1	-	7	1905	6190140
	BC056148.1	-	7	1972	6195844
	HQ692861.1	-	7	1450
	M24898.1	-	7	2077
	X72631.1	-	7	1652

Gene Symbol: THRA
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	M24900.1	-	1	188

More Information

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor, DNA-binding transcription factor, zinc finger transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
glycogen biosynthetic process
transcription initiation from RNA polymerase II promoter
circadian rhythm
proteasomal protein catabolic process
negative regulation of receptor biosynthetic process
regulation of lipid metabolic process
cell differentiation
intracellular receptor signaling pathway
circadian regulation of gene expression
negative regulation of toll-like receptor 4 signaling pathway
regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
regulation of circadian rhythm
steroid hormone mediated signaling pathway
response to leptin
regulation of fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
circadian temperature homeostasis
regulation of insulin secretion involved in cellular response to glucose stimulus
regulation of type B pancreatic cell proliferation
positive regulation of bile acid biosynthetic process
cellular response to lipopolysaccharide
regulation of cholesterol homeostasis
positive regulation of cholesterol homeostasis

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription corepressor binding
steroid hormone receptor activity
transcription corepressor activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
heme binding
transcription regulatory region DNA binding