261

• Gene Symbol: PDK1
• Gene Name: pyruvate dehydrogenase kinase 1
• Gene Aliases: -
• Chromosome Location: Chr.2: 172555373 - 172672693 on Build GRCh38
• UniGene ID: Hs.470633
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDK1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001278549.1	NP_001265478.1	2	498
	NM_002610.4	NP_002601.1	2	498
	NR_103729.1		2	498
	NR_103731.1		2	467
	XM_006712594.2	XP_006712657.1	2	377
	XM_011511343.2	XP_011509645.1	2	260
	XM_011511344.2	XP_011509646.1	2	145
	XM_011511345.2	XP_011509647.1	2	260
	XM_011511347.2	XP_011509649.1	2	145
GenBank mRNA	AK294194.1	-	2	215
	AK302321.1	-	2	468
	AK304388.1	-	2	370
	AK312700.1	-	2	377
	AU118504.2	-	2	416
	BC039158.1	-	2	359	4778360
	DC322401.1	-	2	498
	DQ234350.1	-	2	316
	L42450.1	-	2	440

More Information

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

glucose metabolic process
protein phosphorylation
cell proliferation
intrinsic apoptotic signaling pathway in response to oxidative stress
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of glucose metabolic process
hypoxia-inducible factor-1alpha signaling pathway
mitophagy in response to mitochondrial depolarization

Function(s)

protein kinase activity
pyruvate dehydrogenase (acetyl-transferring) kinase activity
protein binding
ATP binding