273584

• Gene Symbol: NOX4
• Gene Name: NADPH oxidase 4
• Gene Aliases: KOX, KOX-1, RENOX
• Chromosome Location: Chr.11: 89324353 - 89589611 on Build GRCh38
• UniGene ID: Hs.371036
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NOX4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001143836.2	NP_001137308.1	13, 14	1545
	NM_001300995.1	NP_001287924.1	13, 14	1268
	XM_006718849.3	XP_006718912.1	13, 14	1473
GenBank mRNA	AJ704726.1	-	13, 14	1226
	AJ704729.1	-	4, 5	305
	AK291830.1	-	13, 14	1308
	AK298323.1	-	13, 14	1239
	AY288918.1	-	13, 14	1226

More Information

Panther Classification:

Molecular Function -

oxidase

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
cell morphogenesis
response to hypoxia
superoxide metabolic process
inflammatory response
cell aging
negative regulation of cell proliferation
gene expression
positive regulation of smooth muscle cell migration
superoxide anion generation
positive regulation of apoptotic process
positive regulation of MAP kinase activity
bone resorption
homocysteine metabolic process
positive regulation of stress fiber assembly
positive regulation of protein kinase B signaling
cardiac muscle cell differentiation
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to cAMP
cellular response to glucose stimulus
cellular response to gamma radiation
cellular response to transforming growth factor beta stimulus
reactive oxygen species metabolic process
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process

Function(s)

nucleotide binding
protein binding
electron carrier activity
NAD(P)H oxidase activity
superoxide-generating NADPH oxidase activity
oxygen sensor activity
heme binding
flavin adenine dinucleotide binding
modified amino acid binding