273

• Gene Symbol: PFKFB1
• Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
• Gene Aliases: F6PK, HL2K, PFRX
• Chromosome Location: Chr.X: 54933134 - 54998534 on Build GRCh38
• UniGene ID: Hs.444304
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PFKFB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271804.1	NP_001258733.1	2	239
	NM_002625.3	NP_002616.2	2	239
	NR_073450.1		2	239
	XM_017029576.1	XP_016885065.1	2	580
	XM_017029577.1	XP_016885066.1	2	580
	XM_017029578.1	XP_016885067.1	3	662
GenBank mRNA	AK314089.1	-	2	455
	BC096077.1	-	2	251	40000710
	BC096078.2	-	2	241	40000711
	BC096079.3	-	2	240	40000713
	DB187700.1	-	2	455
	JQ425694.1	-	2	183
	JQ425695.1	-	2	183
	X52638.1	-	2	247

More Information

Panther Classification:

Molecular Function -

carbohydrate phosphatase

Gene Ontology Categories:

Process(es)

fructose metabolic process
fructose 2,6-bisphosphate metabolic process
gluconeogenesis
glycolytic process
dephosphorylation
organ regeneration
response to insulin
positive regulation of glucokinase activity
response to glucagon
response to starvation
carbohydrate phosphorylation
response to glucocorticoid
response to cAMP
canonical glycolysis

Function(s)

6-phosphofructo-2-kinase activity
fructose-2,6-bisphosphate 2-phosphatase activity
protein binding
ATP binding
kinase binding
identical protein binding
fructose-6-phosphate binding