278374

Gene Symbol:

SRGAP2B SRGAP2

Gene Name:

SLIT-ROBO Rho GTPase activating protein 2B

SLIT-ROBO Rho GTPase activating protein 2

Gene Aliases:

SRGAP2L, SRGAP2P2

ARHGAP34, FNBP2, SRGAP2A, SRGAP3

Chromosome Location:

Chr.1: 144887191 - 145093441 on Build GRCh38

Chromosome Location:

Chr.1: 206203464 - 206464443 on Build GRCh38

UniGene ID:

Hs.497575

Hs.497575

Species:

Human

Species Specific ID (Flybase ID):

-

-

siRNA Details

Gene Symbol: SRGAP2B
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017002089.1	XP_016857578.1	4, 5	917
	XM_017002091.1	XP_016857580.1	4, 5	917

Gene Symbol: SRGAP2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	XM_017000839.1	XP_016856328.1	1, 2	671

More Information

Panther Classification:

Molecular Function -

GTPase-activating protein

Gene Ontology Categories:

Process(es)

nervous system development
lamellipodium assembly involved in ameboidal cell migration
signal transduction
cell proliferation
extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
substrate adhesion-dependent cell spreading
positive regulation of GTPase activity
filopodium assembly
neuron projection morphogenesis
actin filament severing
regulation of small GTPase mediated signal transduction
negative regulation of cell death
dendritic spine development
negative regulation of neuron migration

Function(s)

GTPase activator activity
protein binding
protein homodimerization activity
Rac GTPase binding