2841

• Gene Symbol: ARHGEF5
• Gene Name: Rho guanine nucleotide exchange factor 5
• Gene Aliases: GEF5, P60, TIM, TIM1
• Chromosome Location: Chr.7: 144355341 - 144380632 on Build GRCh38
• UniGene ID: Hs.334
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_005435.3	NP_005426.2	5, 6	3657
GenBank mRNA	AK090570.1	-	5, 6	1269
	AK123596.1	-	4, 5	1856
	AK160365.1	-	5, 6	3713
	BC010046.2	-	5, 6	602
	BC011839.2	-	5, 6	602
	BC014555.2	-	5, 6	602
	BC136661.1	-	5, 6	3571	9020651
	BX649178.1	-	4, 5	1542
	CR749203.1	-	5, 6	3597
	U02082.1	-	3, 4	398

More Information

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

myeloid dendritic cell chemotaxis
actin cytoskeleton organization
regulation of actin cytoskeleton organization
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of GTPase activity
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of cytoskeleton organization
positive regulation of stress fiber assembly
regulation of ERK1 and ERK2 cascade
positive regulation of podosome assembly
positive regulation of protein import

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
GTP binding
lipid binding