289160

• Gene Symbol: SOD2
• Gene Name: superoxide dismutase 2, mitochondrial
• Gene Aliases: IPO-B, IPOB, MNSOD, MVCD6, Mn-SOD
• Chromosome Location: Chr.6: 159679064 - 159762529 on Build GRCh38
• UniGene ID: Hs.487046
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOD2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000636.3	NP_000627.2	4	670
	NM_001024465.2	NP_001019636.1	4	670
	NM_001024466.2	NP_001019637.1	3	553
	NM_001322814.1	NP_001309743.1	3	553
	NM_001322817.1	NP_001309746.1	6	2199
	NM_001322819.1	NP_001309748.1	4	576
	NM_001322820.1	NP_001309749.1	4	579
GenBank mRNA	AK097395.1	-	6	2196
	AK296809.1	-	3	466
	AK313082.1	-	4	535
	AY280718.1	-	4	506
	AY280719.1	-	3	498
	AY280720.1	-	3	497
	AY280721.1	-	3	497
	BC012423.1	-	4	566	3880111
	BC035422.1	-	4	566
	BM724413.1	-	3	453
	BT006967.1	-	4	509
	DQ003134.1	-	3	506
	M36693.1	-	4	603
	X07834.1	-	4	513
	X14322.1	-	4	604
	X15132.1	-	4	569
	X59445.1	-	4	569
	Y00472.1	-	4	575
	Y00985.1	-	4	603

More Information

Panther Classification:

Molecular Function -

oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

response to reactive oxygen species
response to superoxide
age-dependent response to reactive oxygen species
release of cytochrome c from mitochondria
vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
regulation of transcription from RNA polymerase II promoter
superoxide metabolic process
regulation of blood pressure
negative regulation of cell proliferation
removal of superoxide radicals
oxygen homeostasis
negative regulation of neuron apoptotic process
protein homotetramerization
oxidation-reduction process
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Function(s)

superoxide dismutase activity
manganese ion binding
identical protein binding