3461

• Gene Symbol: MEF2C
• Gene Name: myocyte enhancer factor 2C
• Gene Aliases: C5DELq14.3, DEL5q14.3
• Chromosome Location: Chr.5: 88718241 - 88904105 on Build GRCh38
• UniGene ID: Hs.649965
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: MEF2C
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001193347.1	NP_001180276.1	5	710
	NM_001193350.1	NP_001180279.1	4	932
	NM_001308002.1	NP_001294931.1	3	420
	NM_002397.4	NP_002388.2	4	935
	XM_005248511.2	XP_005248568.1	4	469
	XM_006714619.2	XP_006714682.1	5	791
	XM_006714625.3	XP_006714688.1	4	768
	XM_011543396.2	XP_011541698.1	4	520
	XM_011543400.1	XP_011541702.1	4	707
	XM_011543401.1	XP_011541703.1	4	707
	XM_017009476.1	XP_016864965.1	4	768
	XM_017009477.1	XP_016864966.1	4	707
	XM_017009479.1	XP_016864968.1	4	768
	XM_017009480.1	XP_016864969.1	5	791
	XM_017009481.1	XP_016864970.1	4	469
	XM_017009482.1	XP_016864971.1	4	768
GenBank mRNA	AK312472.1	-	4	640
	AL833268.1	-	5	658
	BC026341.1	-	4	707
	L08895.1	-	4	682
	S57212.1	-		941

More Information

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
blood vessel development
osteoblast differentiation
neuron migration
B cell homeostasis
heart looping
endochondral ossification
blood vessel remodeling
chondrocyte differentiation
germinal center formation
regulation of germinal center formation
primary heart field specification
secondary heart field specification
outflow tract morphogenesis
sinoatrial valve morphogenesis
cardiac ventricle formation
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
humoral immune response
nervous system development
heart development
muscle organ development
skeletal muscle tissue development
muscle cell fate determination
learning or memory
response to virus
positive regulation of gene expression
negative regulation of gene expression
positive regulation of alkaline phosphatase activity
neural crest cell differentiation
cardiac muscle hypertrophy in response to stress
myotube differentiation
neuron differentiation
platelet formation
monocyte differentiation
negative regulation of ossification
melanocyte differentiation
positive regulation of bone mineralization
positive regulation of B cell proliferation
cellular response to drug
skeletal muscle cell differentiation
cellular response to trichostatin A
B cell proliferation
regulation of neuron apoptotic process
negative regulation of neuron apoptotic process
regulation of megakaryocyte differentiation
positive regulation of myoblast differentiation
positive regulation of neuron differentiation
positive regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of neurotransmitter secretion
regulation of synaptic plasticity
positive regulation of skeletal muscle tissue development
neuron development
cell morphogenesis involved in neuron differentiation
embryonic viscerocranium morphogenesis
negative regulation of epithelial cell proliferation
B cell receptor signaling pathway
smooth muscle cell differentiation
positive regulation of muscle cell differentiation
regulation of synapse assembly
regulation of synaptic transmission, glutamatergic
ventricular cardiac muscle cell differentiation
palate development
regulation of synaptic activity
positive regulation of cardiac muscle cell proliferation
excitatory postsynaptic potential
regulation of sarcomere organization
cartilage morphogenesis
regulation of dendritic spine development
renal tubule morphogenesis
cellular response to lipopolysaccharide
cellular response to calcium ion
cellular response to parathyroid hormone stimulus
cellular response to fluid shear stress
cellular response to transforming growth factor beta stimulus
positive regulation of cell proliferation in bone marrow
glomerulus morphogenesis
nephron tubule epithelial cell differentiation
positive regulation of protein homodimerization activity
positive regulation of macrophage apoptotic process
regulation of N-methyl-D-aspartate selective glutamate receptor activity
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of cardiac muscle cell differentiation
positive regulation of behavioral fear response
epithelial cell proliferation involved in renal tubule morphogenesis
positive regulation of skeletal muscle cell differentiation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
AT DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
activating transcription factor binding
miRNA binding
histone deacetylase binding
transcription regulatory region DNA binding
protein heterodimerization activity
HMG box domain binding