35394

• Gene Symbol: BTRC
• Gene Name: beta-transducin repeat containing E3 ubiquitin protein ligase
• Gene Aliases: BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP
• Chromosome Location: Chr.10: 101353808 - 101557321 on Build GRCh38
• UniGene ID: Hs.643802
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: BTRC
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001256856.1	NP_001243785.1	4	474
	NM_003939.4	NP_003930.1	4	444
	NM_033637.3	NP_378663.1	5	552
	XM_006718054.2	XP_006718117.1	5	852
	XM_011540320.2	XP_011538622.1	2	288
	XM_017016870.1	XP_016872359.1	4	774
	XM_017016871.1	XP_016872360.1	5	443
	XM_017016872.1	XP_016872361.1	5	615
	XM_017016873.1	XP_016872362.1	5	471
	XM_017016874.1	XP_016872363.1	3	366
GenBank mRNA	AF101784.1	-	5	404
	AF129530.1	-	4	365
	AK295870.1	-	4	342
	AK313353.1	-	5	425
	AK313417.1	-	4	408
	BC027994.1	-	5	441	5180993
	CR749295.1	-	4	405
	GU727631.1	-	5	441
	KU178451.1	-	5	404
	KU178452.1	-	7	553
	KU178453.1	-	6	497
	KU178454.1	-	4	326
	Y14153.1	-	4	365

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: CB584165.

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
protein dephosphorylation
ubiquitin-dependent protein catabolic process
signal transduction
viral process
Wnt signaling pathway
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
protein destabilization
mammary gland epithelial cell proliferation
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
regulation of circadian rhythm
positive regulation of circadian rhythm
regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of proteolysis
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
T cell receptor signaling pathway
stress-activated MAPK cascade
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
branching involved in mammary gland duct morphogenesis
regulation of canonical Wnt signaling pathway
regulation of proteasomal protein catabolic process
cellular response to organic cyclic compound

Function(s)

ubiquitin-protein transferase activity
protein binding
beta-catenin binding
ligase activity
protein phosphorylated amino acid binding
protein dimerization activity
ubiquitin protein ligase activity