3756

• Gene Symbol: HDAC4
• Gene Name: histone deacetylase 4
• Gene Aliases: AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA
• Chromosome Location: Chr.2: 239048168 - 239401647 on Build GRCh38
• UniGene ID: Hs.20516
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HDAC4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_006037.3	NP_006028.2	20	3283
	XM_006712877.3	XP_006712940.1	19	9229
	XM_006712878.3	XP_006712941.1	20	2803
	XM_006712879.3	XP_006712942.1	19	8696
	XM_006712880.3	XP_006712943.1	19	8708
	XM_011512217.2	XP_011510519.1	19	9244
	XM_011512218.2	XP_011510520.1	19	9229
	XM_011512219.2	XP_011510521.1	19	9214
	XM_011512220.2	XP_011510522.1	19	2983
	XM_011512221.1	XP_011510523.1	20	2971
	XM_011512222.2	XP_011510524.1	20	3272
	XM_011512223.2	XP_011510525.1	20	2786
	XM_011512224.2	XP_011510526.1	19	3174
	XM_011512225.2	XP_011510527.1	19	3159
	XM_011512226.2	XP_011510528.1	19	2731
	XM_011512227.2	XP_011510529.1	18	8258
	XM_011512230.1	XP_011510532.1	14	2169
	XM_017005394.1	XP_016860883.1	18	9113
	XM_017005395.1	XP_016860884.1	16	2035
GenBank mRNA	AB006626.2	-	20	3283
	AF132607.1	-	19	2491
	AK302719.1	-	14	1852
	BC039904.1	-	20	2550	6067363

More Information

Panther Classification:

Molecular Function -

histone modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
skeletal system development
osteoblast development
chromatin remodeling
transcription, DNA-templated
inflammatory response
nervous system development
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of lamellipodium assembly
negative regulation of myotube differentiation
regulation of cardiac muscle contraction by calcium ion signaling
response to denervation involved in regulation of muscle adaptation
cardiac muscle hypertrophy in response to stress
positive regulation of smooth muscle cell migration
chromatin modification
histone deacetylation
B cell differentiation
positive regulation of protein sumoylation
peptidyl-lysine deacetylation
regulation of gene expression, epigenetic
B cell activation
response to drug
regulation of protein binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neuron apoptotic process
negative regulation of osteoblast differentiation
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
regulation of skeletal muscle fiber development
positive regulation of sequence-specific DNA binding transcription factor activity
response to interleukin-1
histone H3 deacetylation
histone H4 deacetylation
cellular response to mechanical stimulus
cellular response to tumor necrosis factor
cellular response to parathyroid hormone stimulus
positive regulation of reactive oxygen species biosynthetic process

Function(s)

RNA polymerase III transcription factor binding
core promoter binding
chromatin binding
transcription corepressor activity
histone deacetylase activity
protein binding
transcription factor binding
zinc ion binding
protein kinase binding
potassium ion binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
activating transcription factor binding
histone deacetylase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
repressing transcription factor binding