382

• Gene Symbol: SYK
• Gene Name: spleen associated tyrosine kinase
• Gene Aliases: p72-Syk
• Chromosome Location: Chr.9: 90801680 - 90898560 on Build GRCh38
• UniGene ID: Hs.371720
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SYK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001135052.3	NP_001128524.1	10	1595
	NM_001174167.2	NP_001167638.1	11	1610
	NM_001174168.2	NP_001167639.1	10	1460
	NM_003177.6	NP_003168.2	11	1664
	XM_005252147.3	XP_005252204.1	11	1575
	XM_011518946.2	XP_011517248.1	11	1524
GenBank mRNA	AK075020.1	-	7	728
	AK290927.1	-	11	1508
	BC001645.2	-	11	1556	2959066
	BC002962.1	-	11	1556	3542895
	BC011399.1	-	10	1444	3870426
	BX647192.1	-	3	3667
	FN391891.1	-	10	1442
	FN391892.1	-	10	1446
	FN391893.1	-	10	1405
	L28824.1	-	11	1556
	S80267.1	-	10	1410
	X73568.1	-	11	1548
	Z29630.1	-	10	1488

More Information

Gene Ontology Categories:

Process(es)

angiogenesis
lymph vessel development
positive regulation of receptor internalization
stimulatory C-type lectin receptor signaling pathway
adaptive immune response
macrophage activation involved in immune response
neutrophil activation involved in immune response
leukocyte activation involved in immune response
serotonin secretion by platelet
protein phosphorylation
inflammatory response
leukocyte cell-cell adhesion
transmembrane receptor protein tyrosine kinase signaling pathway
integrin-mediated signaling pathway
activation of JUN kinase activity
cell proliferation
organ morphogenesis
regulation of platelet activation
regulation of tumor necrosis factor-mediated signaling pathway
viral process
peptidyl-serine phosphorylation
leukotriene biosynthetic process
platelet activation
neutrophil chemotaxis
receptor internalization
positive regulation of type I interferon production
regulation of superoxide anion generation
positive regulation of cell adhesion mediated by integrin
peptidyl-tyrosine autophosphorylation
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
defense response to bacterium
transcription factor import into nucleus
positive regulation of mast cell degranulation
regulation of neutrophil degranulation
beta selection
innate immune response
positive regulation of interleukin-3 biosynthetic process
positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
positive regulation of B cell differentiation
positive regulation of gamma-delta T cell differentiation
positive regulation of bone resorption
positive regulation of alpha-beta T cell differentiation
positive regulation of alpha-beta T cell proliferation
blood vessel morphogenesis
positive regulation of cytokine secretion
positive regulation of peptidyl-tyrosine phosphorylation
regulation of phagocytosis
positive regulation of calcium-mediated signaling
B cell receptor signaling pathway
regulation of sequence-specific DNA binding transcription factor activity
regulation of ERK1 and ERK2 cascade
cellular response to molecule of fungal origin
cellular response to low-density lipoprotein particle stimulus
regulation of arachidonic acid secretion
regulation of platelet aggregation

Function(s)

protein kinase activity
protein serine/threonine kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
integrin binding
protein binding
ATP binding
protein kinase binding