3923

• Gene Symbol: IL10
• Gene Name: interleukin 10
• Gene Aliases: CSIF, GVHDS, IL-10, IL10A, TGIF
• Chromosome Location: Chr.1: 206767603 - 206772494 on Build GRCh38
• UniGene ID: Hs.193717
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: IL10
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000572.2	NP_000563.1	2	241
GenBank mRNA	AF043333.1	-	2	128
	AY029171.1	-	2	182
	BC104252.1	-	2	238	40035920
	BC104253.1	-	2	238	40035922
	CR541993.1	-	2	182
	CR542028.1	-	2	182
	M57627.1	-	2	212

More Information

Gene Ontology Categories:

Process(es)

response to molecule of bacterial origin
negative regulation of cytokine secretion involved in immune response
negative regulation of chronic inflammatory response to antigenic stimulus
positive regulation of B cell apoptotic process
inflammatory response
cytoplasmic sequestering of NF-kappaB
cell-cell signaling
aging
regulation of gene expression
response to activity
response to inactivity
hemopoiesis
B cell differentiation
leukocyte chemotaxis
negative regulation of myeloid dendritic cell activation
negative regulation of B cell proliferation
negative regulation of interferon-gamma production
negative regulation of interleukin-1 production
negative regulation of interleukin-12 production
negative regulation of interleukin-18 production
negative regulation of interleukin-6 production
negative regulation of interleukin-8 production
negative regulation of tumor necrosis factor production
receptor biosynthetic process
response to insulin
response to carbon monoxide
cellular response to hepatocyte growth factor stimulus
type 2 immune response
B cell proliferation
negative regulation of T cell proliferation
response to drug
negative regulation of tumor necrosis factor biosynthetic process
defense response to bacterium
defense response to protozoan
negative regulation of apoptotic process
negative regulation of growth of symbiont in host
negative regulation of nitric oxide biosynthetic process
regulation of isotype switching
negative regulation of MHC class II biosynthetic process
positive regulation of MHC class II biosynthetic process
negative regulation of interferon-alpha biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JAK-STAT cascade
positive regulation of cytokine secretion
negative regulation of membrane protein ectodomain proteolysis
positive regulation of sequence-specific DNA binding transcription factor activity
response to glucocorticoid
regulation of sensory perception of pain
negative regulation of cytokine activity
branching involved in labyrinthine layer morphogenesis
cellular response to lipopolysaccharide
cellular response to estradiol stimulus
negative regulation of chemokine (C-C motif) ligand 5 production
regulation of complement-dependent cytotoxicity
negative regulation of endothelial cell apoptotic process

Function(s)

cytokine activity
interleukin-10 receptor binding
protein binding
growth factor activity