41052

Gene Symbol:

CFLAR C11orf72 HLA-DQB1 ZNF585A

Gene Name:

CASP8 and FADD like apoptosis regulator

chromosome 11 open reading frame 72

major histocompatibility complex, class II, DQ beta 1

zinc finger protein 585A

Gene Aliases:

CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS

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CELIAC1, HLA-DQB, HLA-DRB1, IDDM1

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Chromosome Location:

Chr.2: 201116015 - 201172688 on Build GRCh38

Chromosome Location:

Chr.11: 67602880 - 67606706 on Build GRCh38

Chromosome Location:

Chr.6: 32659464 - 32666689 on Build GRCh38

Chromosome Location:

Chr.19: 37147438 - 37172741 on Build GRCh38

UniGene ID:

Hs.390736

Hs.382074

Hs.409934

Hs.659236

Species:

Human

Species Specific ID (Flybase ID):

-

-

-

-

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001308043.1	NP_001294972.1	5	4289
GenBank mRNA	AB209600.1	-	5	3986

Gene Symbol: C11orf72
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NR_130935.1		3	1436
GenBank mRNA	AK075315.1	-	3	1436

Gene Symbol: HLA-DQB1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	AK097297.1	-	1	1862

Gene Symbol: ZNF585A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
GenBank mRNA	BC026081.2	-	10	1910

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis