4243

• Gene Symbol: PDE2A
• Gene Name: phosphodiesterase 2A
• Gene Aliases: CGS-PDE, PDE2A1, PED2A4, cGSPDE
• Chromosome Location: Chr.11: 72576140 - 72674453 on Build GRCh38
• UniGene ID: Hs.503163
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PDE2A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001143839.3	NP_001137311.1	4	398
	NM_001146209.2	NP_001139681.1	6	448
	NM_001243784.1	NP_001230713.1	5	460
	NM_002599.4	NP_002590.1	5	581
	XM_005274040.2	XP_005274097.1	5	404
GenBank mRNA	AK092278.1	-	5	434
	AK095024.1	-	5	612
	AK312434.1	-	5	543
	AY495087.1	-	6	448
	BC040974.1	-	5	552	5285017
	DA219662.1	-	3	247
	DA227593.1	-	4	398
	DA329075.1	-	5	413
	DA332549.1	-	4	398
	DB068707.1	-	5	443
	U67733.1	-	5	496

More Information

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
cAMP catabolic process
protein targeting to mitochondrion
metabolic process
cAMP-mediated signaling
cGMP-mediated signaling
negative regulation of cAMP biosynthetic process
negative regulation of protein import into nucleus, translocation
cellular response to drug
cellular response to macrophage colony-stimulating factor stimulus
negative regulation of vascular permeability
positive regulation of vascular permeability
cGMP catabolic process
positive regulation of inflammatory response
establishment of endothelial barrier
calcium ion transmembrane transport
cellular response to mechanical stimulus
cellular response to cGMP
cellular response to transforming growth factor beta stimulus

Function(s)

cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
calcium channel activity
protein binding
drug binding
cAMP binding
cGMP binding
TPR domain binding
protein homodimerization activity
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity