45060

• Gene Symbol: SOCS1
• Gene Name: suppressor of cytokine signaling 1
• Gene Aliases: CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
• Chromosome Location: Chr.16: 11254417 - 11256182 on Build GRCh38
• UniGene ID: Hs.50640
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SOCS1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_003745.1	NP_003736.1	2	823
GenBank mRNA	AB000676.1	-	1	627
	AB000734.1	-	2	823
	AB005043.1	-	1	722
	AK127621.1	-	1	1391
	U88326.1	-	1	692

More Information

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

regulation of protein phosphorylation
negative regulation of protein kinase activity
JAK-STAT cascade
regulation of activation of JAK2 kinase activity
protein ubiquitination
cytokine-mediated signaling pathway
organ regeneration
response to estradiol
response to lipopolysaccharide
response to progesterone
regulation of growth
response to drug
negative regulation of tyrosine phosphorylation of Stat1 protein
negative regulation of tyrosine phosphorylation of Stat3 protein
response to peptide hormone
fat cell differentiation
negative regulation of JAK-STAT cascade
negative regulation of insulin receptor signaling pathway
regulation of cytokine secretion
regulation of interferon-gamma-mediated signaling pathway
cellular response to amino acid stimulus

Function(s)

protein kinase inhibitor activity
insulin-like growth factor receptor binding
protein binding
kinase inhibitor activity
protein kinase binding