46080

• Gene Symbol: TANK
• Gene Name: TRAF family member associated NFKB activator
• Gene Aliases: I-TRAF, ITRAF, TRAF2
• Chromosome Location: Chr.2: 161136955 - 161236176 on Build GRCh38
• UniGene ID: Hs.132257
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TANK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001199135.1	NP_001186064.1	2, 3	201
	NM_004180.2	NP_004171.2	2, 3	251
	NM_133484.1	NP_597841.1	2, 3	251
	XM_005246207.3	XP_005246264.2	2, 3	239
	XM_017003093.1	XP_016858582.1	3, 4	432
	XM_017003094.1	XP_016858583.1	4, 5	774
	XM_017003095.1	XP_016858584.1	4, 5	679
	XM_017003096.1	XP_016858585.1	2, 3	233
	XM_017003097.1	XP_016858586.1	4, 5	507
GenBank mRNA	AK313096.1	-	2, 3	201
	BC003388.1	-	1, 2	135
	BC067779.1	-	2, 3	193	5296558
	BT009855.1	-	1, 2	93
	U59863.1	-	2, 3	251
	U63830.1	-	2, 3	250

More Information

Gene Ontology Categories:

Process(es)

proteolysis
cellular response to DNA damage stimulus
signal transduction
I-kappaB kinase/NF-kappaB signaling
TRIF-dependent toll-like receptor signaling pathway
negative regulation of I-kappaB kinase/NF-kappaB signaling
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to ionizing radiation
positive regulation of protein deubiquitination
positive regulation of ubiquitin-specific protease activity

Function(s)

thiol-dependent ubiquitin-specific protease activity
protein binding
ubiquitin protein ligase binding
deubiquitinase activator activity
metal ion binding