49247

• Gene Symbol: Smad1
• Gene Name: SMAD family member 1
• Gene Aliases: Madh1
• Chromosome Location: Chr.19: 32182914 - 32248694 on Build Rnor_6.0
• UniGene ID: Rn.10635
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Smad1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_013130.2	NP_037262.2	5, 6	1348
	XM_006255394.1	XP_006255456.1	5, 6	1494
	XM_006255395.2	XP_006255457.1	5, 6	2153
	XM_006255396.2	XP_006255458.1	5, 6	1384
	XM_006255397.1	XP_006255459.1	5, 6	1473
GenBank mRNA	AF067727.1	-	4, 5	1029
	BC061757.1	-	5, 6	1348	5599977
	U66478.1	-	5, 6	1329

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_008539, AK054104, AK158509, AK017583, AK084505, and others.

Panther Classification:

Molecular Function -

DNA-binding transcription factor, gene-specific transcriptional regulator

Gene Ontology Categories:

Process(es)

MAPK cascade
ureteric bud development
mesodermal cell fate commitment
kidney development
osteoblast fate commitment
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
protein phosphorylation
inflammatory response
transforming growth factor beta receptor signaling pathway
SMAD protein complex assembly
gamete generation
negative regulation of cell proliferation
embryonic pattern specification
response to organonitrogen compound
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
BMP signaling pathway
midbrain development
hindbrain development
wound healing
response to drug
homeostatic process
positive regulation of cell differentiation
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of dendrite morphogenesis
cartilage development
cardiac muscle cell proliferation
bone development
positive regulation of cartilage development
cellular response to organic cyclic compound
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
identical protein binding
protein homodimerization activity
metal ion binding
protein heterodimerization activity
co-SMAD binding
I-SMAD binding