512 Validated

• Gene Symbol: CSK
• Gene Name: c-src tyrosine kinase
• Gene Aliases: -
• Chromosome Location: Chr.15: 74782064 - 74803198 on Build GRCh38
• UniGene ID: Hs.77793
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CSK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127190.1	NP_001120662.1	14	1894
	NM_004383.2	NP_004374.1	13	2413
	XM_005254165.4	XP_005254222.1	13	1863
	XM_017021925.1	XP_016877414.1	13	2454
GenBank mRNA	AK127672.1	-	15	2143
	AK290531.1	-	14	1885
	AY007162.1	-	11	1643
	BC104847.1	-	13	1871	8143850
	BC104875.1	-	13	1871	8143878
	BC106073.1	-	13	2413	6526810
	X59932.1	-	13	1844
	X60114.1	-	13	2123

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001030039, XM_006243163, XM_006243164, X58631, FQ227277, and others.
This siRNA also targets the following transcripts in Mouse: AK194012, AK219690, AK013057, AK170815, BC095962, and others.

Matching Taqman Gene Expression Assay:

Hs00177843_m1

Gene Ontology Categories:

Process(es)

regulation of cytokine production
adaptive immune response
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
epidermal growth factor receptor signaling pathway
central nervous system development
brain development
negative regulation of cell proliferation
negative regulation of low-density lipoprotein particle clearance
cell migration
cell differentiation
T cell costimulation
negative regulation of interleukin-6 production
negative regulation of kinase activity
adherens junction organization
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
negative regulation of Golgi to plasma membrane protein transport
positive regulation of MAP kinase activity
innate immune response
negative regulation of bone resorption
oligodendrocyte differentiation
negative regulation of phagocytosis
T cell receptor signaling pathway
regulation of Fc receptor mediated stimulatory signaling pathway
negative regulation of ERK1 and ERK2 cascade
cellular response to peptide hormone stimulus

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding
protein C-terminus binding
kinase activity
protein phosphatase binding
protein kinase A catalytic subunit binding
identical protein binding
metal ion binding
proline-rich region binding