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Gene Symbol:
Apex1
Gene Name:
APEX nuclease (multifunctional DNA repair enzyme) 1
Gene Aliases:
APE, Apex, REF-1
Chromosome Location:
Chr.15: 27849943 - 27852083 on Build Rnor_6.0
UniGene ID:
Rn.5949
Species:
Rat
Species Specific ID (Flybase ID):
-
siRNA ID 52762

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Catalog # AM16708
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Apex1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_024148.1 NP_077062.1 5 785
XM_006251913.1 XP_006251975.1 5 826
GenBank mRNA AF309114.1 - 4 701
AF311054.1 - 4 594
BC078816.1 - 5 793 7127205
D44495.1 - 5 785
FQ220521.1 - 5 787
L27076.1 - 5 769

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_009687, D90374, AK212859, BC052401, AK013296.

Gene Ontology Categories:

Function(s) Process(es)

DNA catabolic process, endonucleolytic
DNA catabolic process, exonucleolytic
DNA repair
base-excision repair
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
aging
response to organonitrogen compound
negative regulation of smooth muscle cell migration
response to drug
regulation of mRNA stability
cell redox homeostasis
positive regulation of DNA repair
oxidation-reduction process
cellular response to hydrogen peroxide
cellular response to cAMP
cellular response to peptide hormone stimulus
cellular response to organonitrogen compound
DNA demethylation
nucleic acid phosphodiester bond hydrolysis
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of G1/S transition of mitotic cell cycle
DNA binding
damaged DNA binding
transcription coactivator activity
DNA-(apurinic or apyrimidinic site) lyase activity
endonuclease activity
endoribonuclease activity
protein binding
phosphoric diester hydrolase activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
3'-5' exonuclease activity
oxidoreductase activity
site-specific endodeoxyribonuclease activity, specific for altered base
chromatin DNA binding
protein complex binding
poly(A) RNA binding
metal ion binding
NF-kappaB binding

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