55514

• Gene Symbol: Tdg
• Gene Name: thymine-DNA glycosylase
• Gene Aliases: -
• Chromosome Location: Chr.7: 27194000 - 27213676 on Build Rnor_6.0
• UniGene ID: Rn.98685
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Tdg
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053729.1	NP_446181.1	2, 3	216
GenBank mRNA	AY026945.1	-	2, 3	216
	BC129088.1	-	2, 3	233	8362408

More Information

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
base-excision repair
mismatch repair
transcription from RNA polymerase II promoter
negative regulation of protein binding
negative regulation of chromatin binding
regulation of gene expression, epigenetic
DNA demethylation

Function(s)

RNA polymerase II transcription cofactor activity
double-stranded DNA binding
protein kinase C binding
transcription factor binding
pyrimidine-specific mismatch base pair DNA N-glycosylase activity
hydrolase activity, hydrolyzing N-glycosyl compounds
DNA N-glycosylase activity
protein domain specific binding
mismatched DNA binding
SUMO binding
protein homodimerization activity
structure-specific DNA binding