55669

• Gene Symbol: Chek2
• Gene Name: checkpoint kinase 2
• Gene Aliases: Chk2, Rad53
• Chromosome Location: Chr.12: 51845574 - 51878097 on Build Rnor_6.0
• UniGene ID: Rn.163213
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Chek2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_053677.1	NP_446129.1	5	754
	XM_006249518.2	XP_006249580.1	6	868
	XM_006249519.2	XP_006249581.1	5	747
	XM_006249520.2	XP_006249582.1	5	804
	XM_006249521.2	XP_006249583.1	5	688
	XM_008769308.1	XP_008767530.1	5	747
GenBank mRNA	AF134054.1	-	5	754

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_016681, BC056617, AK044913, AF086905.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
G2/M transition of mitotic cell cycle
double-strand break repair
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage
response to gamma radiation
regulation of protein catabolic process
signal transduction in response to DNA damage
cellular protein catabolic process
positive regulation of transcription, DNA-templated
protein autophosphorylation
protein stabilization
signal transduction involved in intra-S DNA damage checkpoint
mitotic spindle assembly

Function(s)

protein kinase activity
protein serine/threonine kinase activity
ATP binding
kinase activity
protein kinase binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity