59099

• Gene Symbol: Igf1
• Gene Name: insulin-like growth factor 1
• Gene Aliases: -
• Chromosome Location: Chr.7: 28412123 - 28491815 on Build Rnor_6.0
• UniGene ID: Rn.201887
• Species: Rat
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Igf1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001082477.2	NP_001075946.2	5	482
	NM_001082478.1	NP_001075947.1	5	779
	NM_001082479.1	NP_001075948.1	4	727
	NM_178866.4	NP_849197.3	4	430
	XM_006241191.2	XP_006241253.1	6	623
	XM_006241192.1	XP_006241254.1	6	537
	XM_006241193.2	XP_006241255.1	5	570
	XM_006241194.2	XP_006241256.1	5	661
GenBank mRNA	BC086374.1	-	4	430	7300903
	D00698.1	-	4	411
	FQ209824.1	-	5	559
	FQ210560.1	-	5	495
	FQ210688.1	-	4	443
	FQ220385.1	-	5	803
	FQ225388.1	-	4	443
	FQ225437.1	-	5	443
	FQ231951.1	-	4	443
	FQ234943.1	-	4	443
	M15480.1	-	5	526
	M15481.1	-	4	1162
	M17335.1	-	4	627
	X06043.1	-	3	312
	X06107.1	-	5	757
	X06108.1	-	6	571

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Mouse: NM_010512, NM_001111276, NM_001111275, NM_001111274, AK081019, and others.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

cell activation
regulation of protein phosphorylation
blood vessel remodeling
regulation of translation
nervous system development
female pregnancy
memory
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
response to heat
response to mechanical stimulus
glial cell differentiation
response to organic substance
regulation of gene expression
positive regulation of cardiac muscle hypertrophy
positive regulation of phosphatidylinositol 3-kinase signaling
response to organic cyclic compound
response to activity
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
muscle hypertrophy
myotube cell development
positive regulation of smooth muscle cell migration
positive regulation of cerebellar granule cell precursor proliferation
water homeostasis
proteoglycan biosynthetic process
positive regulation of cell growth
lung development
mammary gland development
exocrine pancreas development
response to nutrient levels
response to lipopolysaccharide
regulation of establishment or maintenance of cell polarity
positive regulation of protein import into nucleus, translocation
negative regulation of smooth muscle cell apoptotic process
multicellular organism growth
bone mineralization involved in bone maturation
regulation of multicellular organism growth
positive regulation of activated T cell proliferation
regulation of cell proliferation
positive regulation of tyrosine phosphorylation of Stat5 protein
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of DNA binding
positive regulation of MAPK cascade
positive regulation of insulin-like growth factor receptor signaling pathway
myoblast differentiation
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of glycogen biosynthetic process
positive regulation of DNA replication
positive regulation of glycolytic process
positive regulation of mitotic nuclear division
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glucose import
positive regulation of Ras protein signal transduction
insulin-like growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of fibroblast proliferation
lung alveolus development
cell development
response to steroid hormone
positive regulation of smooth muscle cell proliferation
branching morphogenesis of an epithelial tube
inner ear development
chondroitin sulfate proteoglycan biosynthetic process
positive regulation of epithelial cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
detection of mechanical stimulus involved in sensory perception
regulation of protein metabolic process
response to glucocorticoid
myoblast proliferation
positive regulation of protein kinase B signaling
regulation of calcium ion transport
negative regulation of oocyte development
lung vasculature development
lung lobe morphogenesis
Type I pneumocyte differentiation
Type II pneumocyte differentiation
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
prostate gland growth
prostate gland epithelium morphogenesis
prostate gland stromal morphogenesis
negative regulation of androgen receptor signaling pathway
negative regulation of ERK1 and ERK2 cascade
positive regulation of calcineurin-NFAT signaling cascade
cellular response to electrical stimulus
positive regulation of protein serine/threonine kinase activity
positive regulation of steroid hormone biosynthetic process
negative regulation of release of cytochrome c from mitochondria
extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of neuron death
positive regulation of myoblast proliferation
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

insulin receptor binding
insulin-like growth factor receptor binding
integrin binding
hormone activity
steroid binding
protein binding
growth factor activity
protein serine/threonine kinase activator activity