5927

• Gene Symbol: PPP3CB
• Gene Name: protein phosphatase 3 catalytic subunit beta
• Gene Aliases: CALNA2, CALNB, CNA2, PP2Bbeta
• Chromosome Location: Chr.10: 73436428 - 73496024 on Build GRCh38
• UniGene ID: Hs.500067
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PPP3CB
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001142353.2	NP_001135825.1	2	295
	NM_001142354.2	NP_001135826.1	2	295
	NM_001289968.1	NP_001276897.1	2	295
	NM_001289969.1	NP_001276898.1	3	414
	NM_021132.3	NP_066955.1	2	295
	XM_005269944.1	XP_005270001.1	2	295
	XM_017016379.1	XP_016871868.1	2	295
GenBank mRNA	AJ488506.1	-	2	232
	AK301582.1	-	3	321
	BC028049.1	-	2	283	4538822
	BC035464.1	-	2	253
	DA128707.1	-	2	295
	DA192735.1	-	2	295
	DA854064.1	-	2	295
	M29550.1	-	2	267
	M29551.1	-	2	276

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017042, M31809, D90036.
This siRNA also targets the following transcripts in Mouse: NM_008914, M81483, AB221678, BC066000, BC037668, and others.

Panther Classification:

Molecular Function -

protein phosphatase

Gene Ontology Categories:

Process(es)

negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
signal transduction
Wnt signaling pathway, calcium modulating pathway
heart development
learning
memory
dephosphorylation
calcium ion regulated exocytosis
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
social behavior
cellular response to drug
positive regulation of insulin secretion involved in cellular response to glucose stimulus
Fc-epsilon receptor signaling pathway
T cell proliferation
T cell activation
T cell homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
axon extension
regulation of insulin secretion
positive regulation of NFAT protein import into nucleus

Function(s)

protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
drug binding
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
protein dimerization activity