60248

• Gene Symbol: Blm
• Gene Name: Bloom syndrome, RecQ helicase-like
• Gene Aliases: -
• Chromosome Location: Chr.7: 80454993 - 80535119 on Build GRCm38
• UniGene ID: Mm.12932
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Blm
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001042527.2	NP_001035992.1	3	218
	NM_007550.4	NP_031576.4	3	489
GenBank mRNA	AB008674.1	-	3	479
	AK137022.1	-	3	200
	AK157898.1	-	3	219
	AK164605.1	-	3	187
	BB614580.1	-	3	490
	BB655193.1	-	3	208
	Z98263.1	-	3	196

More Information

Panther Classification:

Molecular Function -

DNA helicase

Gene Ontology Categories:

Process(es)

regulation of cyclin-dependent protein serine/threonine kinase activity
telomere maintenance
DNA double-strand break processing
DNA strand renaturation
DNA replication
DNA repair
DNA recombination
cellular response to DNA damage stimulus
mitotic G2 DNA damage checkpoint
response to X-ray
replication fork processing
DNA duplex unwinding
cellular metabolic process
positive regulation of transcription, DNA-templated
negative regulation of DNA recombination
negative regulation of mitotic recombination
alpha-beta T cell differentiation
positive regulation of alpha-beta T cell proliferation
regulation of binding
protein oligomerization
chromosome organization
negative regulation of cell division
negative regulation of thymocyte apoptotic process
cellular response to ionizing radiation
cellular response to hydroxyurea
cellular response to camptothecin

Function(s)

nucleotide binding
bubble DNA binding
p53 binding
nucleic acid binding
DNA binding
single-stranded DNA binding
catalytic activity
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
ATP-dependent helicase activity
four-way junction helicase activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
ATPase activity
annealing helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding