61074

• Gene Symbol: Dnmt3a
• Gene Name: DNA methyltransferase 3A
• Gene Aliases: MmuIIIA
• Chromosome Location: Chr.12: 3804535 - 3914443 on Build GRCm38
• UniGene ID: Mm.470389
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Dnmt3a
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001271753.1	NP_001258682.1	8	1184
	NM_007872.4	NP_031898.1	8	1230
	NM_153743.4	NP_714965.1	3	408
GenBank mRNA	AF068625.2	-	8	1134
	AF480164.1	-	3	408
	AK077792.1	-	3	373
	AK090132.1	-	8	1161
	AK136170.1	-	3	330
	AK147263.1	-	8	1184
	AK147627.1	-	8	1184
	AK147642.1	-	8	1184
	AK147676.1	-	8	1159
	AK157792.1	-	3	379
	BC007466.1	-	8	1162	3492853
	BE855330.1	-	3	408

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001003957, NM_001003958, XM_008764531, XM_008764530, BC089916.

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA methylation
methylation-dependent chromatin silencing
regulation of gene expression by genetic imprinting
transcription, DNA-templated
regulation of transcription, DNA-templated
spermatogenesis
maintenance of DNA methylation
DNA methylation on cytosine within a CG sequence
positive regulation of cell death
chromatin modification
methylation
DNA methylation on cytosine
DNA methylation involved in embryo development
DNA methylation involved in gamete generation
hypermethylation of CpG island
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
cellular response to amino acid stimulus
C-5 methylation of cytosine

Function(s)

DNA binding
chromatin binding
DNA (cytosine-5-)-methyltransferase activity
protein binding
methyltransferase activity
transferase activity
identical protein binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates