64927

• Gene Symbol: Top1
• Gene Name: topoisomerase (DNA) I
• Gene Aliases: AI467334, D130064I21Rik, Top-1
• Chromosome Location: Chr.2: 160645897 - 160722764 on Build GRCm38
• UniGene ID: Mm.217233
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Top1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_009408.2	NP_033434.2	3	449
GenBank mRNA	AK145538.1	-	3	459
	AK160590.1	-	3	303
	AK164061.1	-	3	368
	BC002095.1	-	3	330
	BC048743.1	-	3	344
	BC092349.1	-	3	279
	D10061.1	-	3	116
	L20632.1	-	3	116

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022615, XM_008759598, AY325188, AF140782.

Panther Classification:

Molecular Function -

DNA topoisomerase

Gene Ontology Categories:

Process(es)

DNA replication
DNA topological change
chromatin remodeling
chromosome segregation
rRNA transcription
circadian regulation of gene expression
embryonic cleavage
rhythmic process

Function(s)

core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase activity
DNA topoisomerase type I activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
isomerase activity
chromatin DNA binding
protein complex binding
poly(A) RNA binding