71499

• Gene Symbol: Txk
• Gene Name: TXK tyrosine kinase
• Gene Aliases: A130089B16Rik, Btkl, PTK-RL-18, PTK4, Rlk
• Chromosome Location: Chr.5: 72695978 - 72752992 on Build GRCm38
• UniGene ID: Mm.3264
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Txk
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001122754.2	NP_001116226.1	7, 8	672
	NM_001289494.1	NP_001276423.1	6, 7	606
	NM_001289495.1	NP_001276424.1	7, 8	689
	NM_013698.3	NP_038726.2	6, 7	756
GenBank mRNA	AK088209.1	-	6, 7	602
	AK138069.1	-	7, 8	669
	AK138786.1	-	7, 8	686
	BC120552.1	-	6, 7	659	40129475
	BC137710.1	-	6, 7	661	8860729
	D43963.1	-	6, 7	756
	D83201.1	-	6, 7	696
	D83202.1	-	6, 7	859
	U16145.1	-	7, 8	637
	U19607.1	-	7, 8	672

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001024255, XM_008770142, XM_008770141, BC095847.

Gene Ontology Categories:

Process(es)

cytokine production
NK T cell differentiation
adaptive immune response
immune system process
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
activation of phospholipase C activity
phosphorylation
interferon-gamma production
interleukin-4 production
positive regulation of interferon-gamma production
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
T cell receptor signaling pathway
positive regulation of interferon-gamma-mediated signaling pathway

Function(s)

nucleotide binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II regulatory region DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups