9253

• Gene Symbol: PRLR
• Gene Name: prolactin receptor
• Gene Aliases: HPRL, MFAB, hPRLrI
• Chromosome Location: Chr.5: 35048295 - 35230589 on Build GRCh38
• UniGene ID: Hs.368587
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: PRLR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000949.6	NP_000940.1	4	598
	NM_001204315.1	NP_001191244.1	3	276
	NM_001204316.1	NP_001191245.1	3	276
	NM_001204317.1	NP_001191246.1	3	276
	NM_001204318.1	NP_001191247.1	3	276
	XM_006714484.2	XP_006714547.1	4	416
	XM_011514068.2	XP_011512370.1	4	431
	XM_011514069.2	XP_011512371.1	4	370
	XM_017009646.1	XP_016865135.1	2	214
GenBank mRNA	AF166329.1	-	2	171
	AF416618.1	-	2	188
	AF416619.1	-	2	188
	AF492470.1	-	2	188
	AK313270.1	-	4	486
	BC059392.1	-	4	484	30343995
	DA640476.1	-	4	431
	GU133399.1	-	2	188
	KJ651922.1	-	5	600
	KJ651923.1	-	5	548
	KJ651924.1	-	4	457
	KJ651925.1	-	4	464
	M31661.1	-	4	455
	S78505.1	-	1	99

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_012630, NM_001034111, XM_008760751, M57668, U07567, and others.

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

steroid biosynthetic process
cell surface receptor signaling pathway
activation of transmembrane receptor protein tyrosine kinase activity
embryo implantation
lactation
regulation of cell adhesion
regulation of epithelial cell differentiation
prolactin signaling pathway
T cell activation
activation of JAK2 kinase activity
negative regulation of apoptotic process
JAK-STAT cascade involved in growth hormone signaling pathway
mammary gland epithelial cell differentiation
prostate gland growth
mammary gland alveolus development

Function(s)

prolactin receptor activity
protein binding
peptide hormone binding
protein homodimerization activity
ornithine decarboxylase activator activity
metal ion binding