HSS113587

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• UniGene ID: Hs.743352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162383.1	NP_001155855.1	15	1965
	NM_001162384.1	NP_001155856.1	15	1962
	NM_004723.3	NP_004714.2	15	1890
	XM_005245587.2	XP_005245644.1	15	2018
	XM_005245588.2	XP_005245645.1	15	2015
	XM_005245589.4	XP_005245646.1	15	2171
	XM_005245590.3	XP_005245647.1	15	1893
	XM_005245591.3	XP_005245648.1	16	2009
	XM_005245592.2	XP_005245649.1	15	2162
	XM_005245593.4	XP_005245650.1	15	1893
	XM_005245594.2	XP_005245651.1	15	2879
	XM_006711622.3	XP_006711685.1	15	3156
	XM_006711623.3	XP_006711686.1	14	1892
	XM_006711624.3	XP_006711687.1	14	1919
	XM_006711625.3	XP_006711688.1	14	1825
	XM_006711626.2	XP_006711689.1	14	2811
	XM_011510136.2	XP_011508438.2	19	2574
	XM_011510137.2	XP_011508439.2	19	2577
	XM_011510139.2	XP_011508441.1	19	2577
	XM_011510141.2	XP_011508443.1	15	2695
	XM_011510143.2	XP_011508445.1	11	1441
	XM_017002794.1	XP_016858283.1	19	2574
	XM_017002795.1	XP_016858284.1	15	1909
	XM_017002796.1	XP_016858285.1	15	3153
	XM_017002797.1	XP_016858286.1	15	1893
	XM_017002798.1	XP_016858287.1	14	3088
	XM_017002799.1	XP_016858288.1	14	1889
GenBank mRNA	AB014551.3	-	19	2233
	AF486838.1	-	15	1844
	AL512715.1	-	15	1875
	BC020567.1	-	15	1947	4157775
	BT007407.1	-	14	1766

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding