HSS113589

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• UniGene ID: Hs.743352
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001162383.1	NP_001155855.1	8, 9	1083
	NM_001162384.1	NP_001155856.1	8, 9	1080
	NM_004723.3	NP_004714.2	8, 9	1008
	XM_005245587.2	XP_005245644.1	8, 9	1136
	XM_005245588.2	XP_005245645.1	8, 9	1133
	XM_005245589.4	XP_005245646.1	8, 9	1289
	XM_005245590.3	XP_005245647.1	8, 9	1011
	XM_005245591.3	XP_005245648.1	9, 10	1127
	XM_005245592.2	XP_005245649.1	8, 9	1280
	XM_005245593.4	XP_005245650.1	8, 9	1011
	XM_005245594.2	XP_005245651.1	8, 9	1997
	XM_006711622.3	XP_006711685.1	8, 9	2274
	XM_006711623.3	XP_006711686.1	7, 8	1010
	XM_006711624.3	XP_006711687.1	7, 8	1037
	XM_006711625.3	XP_006711688.1	7, 8	943
	XM_006711626.2	XP_006711689.1	7, 8	1929
	XM_011510136.2	XP_011508438.2	12, 13	1692
	XM_011510137.2	XP_011508439.2	12, 13	1695
	XM_011510139.2	XP_011508441.1	12, 13	1695
	XM_011510141.2	XP_011508443.1	8, 9	1813
	XM_011510143.2	XP_011508445.1	4, 5	559
	XM_017002794.1	XP_016858283.1	12, 13	1692
	XM_017002795.1	XP_016858284.1	8, 9	1027
	XM_017002796.1	XP_016858285.1	8, 9	2271
	XM_017002797.1	XP_016858286.1	8, 9	1011
	XM_017002798.1	XP_016858287.1	7, 8	2206
	XM_017002799.1	XP_016858288.1	7, 8	1007
GenBank mRNA	AB014551.3	-	12, 13	1351
	AF486838.1	-	8, 9	962
	AK295924.1	-	8, 9	1280
	AK304548.1	-	11, 12	1420
	AL512715.1	-	8, 9	993
	BC020567.1	-	8, 9	1065	4157775
	BT007407.1	-	7, 8	884
	U72206.1	-	8, 9	1070

More Information

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding