HSS118041

• Gene Symbol: CNOT1
• Gene Name: CCR4-NOT transcription complex subunit 1
• Gene Aliases: AD-005, CDC39, NOT1, NOT1H
• Chromosome Location: Chr.16: 58519946 - 58629886 on Build GRCh38
• UniGene ID: Hs.460923
• Species: Human

siRNA Details

Gene Symbol: CNOT1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001265612.1	NP_001252541.1	3	461
	NM_016284.4	NP_057368.3	3	461
	NM_206999.2	NP_996882.1	3	461
	NR_049763.1		3	461
GenBank mRNA	AK056927.1	-	3	407
	AK300281.1	-	3	406
	AL832769.1	-	3	410
	AL833549.1	-	3	421
	BC040523.1	-	3	413	5266600
	BX537840.1	-	3	407
	BX647815.1	-	3	401
	DB456343.1	-	3	461
	EF553522.1	-	3	410

More Information

Panther Classification:

Molecular Function -

mRNA polyadenylation factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
nuclear-transcribed mRNA poly(A) tail shortening
transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
multicellular organism development
positive regulation of cytoplasmic mRNA processing body assembly
negative regulation of translation
negative regulation of intracellular estrogen receptor signaling pathway
gene silencing by miRNA
negative regulation of retinoic acid receptor signaling pathway
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
positive regulation of mRNA catabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
regulation of stem cell population maintenance

Function(s)

poly(A)-specific ribonuclease activity
protein binding
protein domain specific binding
estrogen receptor binding
protein complex scaffold
retinoic acid receptor binding
poly(A) RNA binding
armadillo repeat domain binding