HSS118597

• Gene Symbol: NEDD4L
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Gene Aliases: NEDD4-2, NEDD4.2, RSP5, hNEDD4-2
• Chromosome Location: Chr.18: 58044362 - 58401540 on Build GRCh38
• UniGene ID: Hs.185677
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NEDD4L
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001144964.1	NP_001138436.1	19	1981
	NM_001144965.1	NP_001138437.1	19	1933
	NM_001144966.2	NP_001138438.1	18	1858
	NM_001144967.2	NP_001138439.1	19	2027
	NM_001144968.1	NP_001138440.1	19	1923
	NM_001144969.1	NP_001138441.1	18	1863
	NM_001144970.2	NP_001138442.1	17	1906
	NM_001144971.1	NP_001138443.1	19	1951
	NM_001243960.1	NP_001230889.1	17	1835
	NM_015277.5	NP_056092.2	18	1967
	XM_005266658.4	XP_005266715.2	16	1958
	XM_005266660.4	XP_005266717.2	15	1902
	XM_005266663.4	XP_005266720.2	14	1842
	XM_006722421.3	XP_006722484.2	15	1897
	XM_006722424.3	XP_006722487.2	12	1450
	XM_006722425.3	XP_006722488.2	11	1394
	XM_006722426.3	XP_006722489.1	21	2175
	XM_006722428.3	XP_006722491.1	20	2097
	XM_006722430.3	XP_006722493.1	19	2005
	XM_011525887.2	XP_011524189.1	21	2155
	XM_017025676.1	XP_016881165.1	13	1647
	XM_017025677.1	XP_016881166.1	12	1591
	XM_017025678.1	XP_016881167.1	19	2036
	XM_017025679.1	XP_016881168.1	18	1951
	XM_017025680.1	XP_016881169.1	15	1639
	XM_017025681.1	XP_016881170.1	14	1441
GenBank mRNA	AB007899.1	-	17	1806
	AB071179.1	-	18	1798
	AF210730.1	-	18	1758
	AF385931.1	-	19	1982
	AK294963.1	-	17	1855
	AL137469.1	-	14	1279
	AY112983.1	-	19	1933
	AY112984.2	-	19	1923
	AY112985.2	-	18	1867
	AY312514.1	-	19	1744
	AY751751.1	-	7	736
	BC000621.2	-	13	1384
	BC019345.1	-	13	1384
	BC032597.1	-	17	1862	5528964
	DQ181796.1	-	19	1951

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
regulation of membrane depolarization
protein monoubiquitination
sodium ion transport
cellular sodium ion homeostasis
excretion
response to metal ion
protein ubiquitination
viral life cycle
water homeostasis
ion transmembrane transport
regulation of ion transmembrane transport
regulation of protein catabolic process
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
positive regulation of endocytosis
regulation of membrane repolarization
protein K48-linked ubiquitination
ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of sodium ion transmembrane transport
positive regulation of dendrite extension
negative regulation of protein localization to cell surface
negative regulation of sodium ion transmembrane transporter activity
positive regulation of caveolin-mediated endocytosis

Function(s)

ubiquitin-protein transferase activity
protein binding
potassium channel regulator activity
ligase activity
sodium channel regulator activity
potassium channel inhibitor activity
sodium channel inhibitor activity
ion channel binding