HSS118598

• Gene Symbol: NEDD4L
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
• Gene Aliases: NEDD4-2, NEDD4.2, RSP5, hNEDD4-2
• Chromosome Location: Chr.18: 58044362 - 58401540 on Build GRCh38
• UniGene ID: Hs.185677
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: NEDD4L
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001144964.1	NP_001138436.1	22	2388
	NM_001144965.1	NP_001138437.1	22	2340
	NM_001144966.2	NP_001138438.1	21	2265
	NM_001144967.2	NP_001138439.1	22	2434
	NM_001144968.1	NP_001138440.1	22	2330
	NM_001144969.1	NP_001138441.1	21	2270
	NM_001144970.2	NP_001138442.1	20	2313
	NM_001144971.1	NP_001138443.1	22	2358
	NM_001243960.1	NP_001230889.1	20	2242
	NM_015277.5	NP_056092.2	21	2374
	XM_005266658.4	XP_005266715.2	19	2365
	XM_005266660.4	XP_005266717.2	18	2309
	XM_005266663.4	XP_005266720.2	17	2249
	XM_006722421.3	XP_006722484.2	18	2304
	XM_006722424.3	XP_006722487.2	15	1857
	XM_006722425.3	XP_006722488.2	14	1801
	XM_006722426.3	XP_006722489.1	24	2582
	XM_006722428.3	XP_006722491.1	23	2504
	XM_006722430.3	XP_006722493.1	22	2412
	XM_011525887.2	XP_011524189.1	24	2562
	XM_017025676.1	XP_016881165.1	16	2054
	XM_017025677.1	XP_016881166.1	15	1998
	XM_017025678.1	XP_016881167.1	22	2443
	XM_017025679.1	XP_016881168.1	21	2358
	XM_017025680.1	XP_016881169.1	18	2046
	XM_017025681.1	XP_016881170.1	17	1848
GenBank mRNA	AB007899.1	-	20	2213
	AB071179.1	-	21	2205
	AF210730.1	-	21	2165
	AF385931.1	-	22	2389
	AK294963.1	-	21	2265
	AK300444.1	-	21	2216
	AL137469.1	-	17	1686
	AY112983.1	-	22	2340
	AY112984.2	-	22	2330
	AY112985.2	-	21	2274
	AY312514.1	-	22	2151
	BC000621.2	-	16	1791
	BC019345.1	-	16	1791
	BC032597.1	-	20	2269	5528964
	DQ181796.1	-	22	2358

More Information

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
regulation of membrane depolarization
protein monoubiquitination
sodium ion transport
cellular sodium ion homeostasis
excretion
response to metal ion
protein ubiquitination
viral life cycle
water homeostasis
ion transmembrane transport
regulation of ion transmembrane transport
regulation of protein catabolic process
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
positive regulation of endocytosis
regulation of membrane repolarization
protein K48-linked ubiquitination
ventricular cardiac muscle cell action potential
regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transporter activity
negative regulation of potassium ion transmembrane transport
negative regulation of sodium ion transmembrane transport
positive regulation of dendrite extension
negative regulation of protein localization to cell surface
negative regulation of sodium ion transmembrane transporter activity
positive regulation of caveolin-mediated endocytosis

Function(s)

ubiquitin-protein transferase activity
protein binding
potassium channel regulator activity
ligase activity
sodium channel regulator activity
potassium channel inhibitor activity
sodium channel inhibitor activity
ion channel binding