HSS133566

• Gene Symbol: SPPL3
• Gene Name: signal peptide peptidase like 3
• Gene Aliases: IMP2, MDHV1887, PRO4332, PSH1, PSL4
• Chromosome Location: Chr.12: 120762510 - 120904352 on Build GRCh38
• UniGene ID: Hs.507087
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SPPL3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_139015.4	NP_620584.2	3, 4	674
	XM_011537925.2	XP_011536227.1	3, 4	204
GenBank mRNA	AB252457.1	-	3, 4	266
	AJ345030.1	-	3, 4	242
	AK074916.1	-	2, 3	157
	AK223590.1	-	3, 4	670
	AK291161.1	-	3, 4	496
	AY169313.1	-	3, 4	448
	BC073910.1	-	3, 4	455	4538522
	BC101625.1	-	3, 4	269	8069131
	BC101627.1	-	3, 4	269	8069133
	BU932077.1	-	3, 4	674

More Information

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

signal peptide processing
membrane protein ectodomain proteolysis
positive regulation of cytosolic calcium ion concentration
positive regulation of protein binding
membrane protein proteolysis
positive regulation of protein dephosphorylation
T cell receptor signaling pathway
positive regulation of NFAT protein import into nucleus
positive regulation of calcineurin-NFAT signaling cascade

Function(s)

protein binding
aspartic endopeptidase activity, intramembrane cleaving
protein homodimerization activity