HSS173925

• Gene Symbol: HPSE
• Gene Name: heparanase
• Gene Aliases: HPA, HPA1, HPR1, HPSE1, HSE1
• Chromosome Location: Chr.4: 83292461 - 83335153 on Build GRCh38
• UniGene ID: Hs.44227
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HPSE
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001098540.2	NP_001092010.1	8, 9	1188
	NM_001199830.1	NP_001186759.1	7, 8	946
	NM_006665.5	NP_006656.2	9, 10	1226
GenBank mRNA	AF084467.1	-	8, 9	1095
	AF144325.1	-	8, 9	1188
	AF152376.1	-	8, 9	1103
	AF155510.1	-	9, 10	1225
	AF165154.1	-	8, 9	1140
	AJ627581.1	-	2, 3	231
	AK075400.1	-	8, 9	1152
	AK222986.1	-	8, 9	1154
	AM419200.1	-	7, 8	915
	AY948074.1	-	8, 9	1094
	BC051321.1	-	9, 10	1226	6250265
	FJ517659.1	-	8, 9	1057
	FJ517660.1	-	7, 8	883

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_022605, AF184967, AF359508.
This siRNA also targets the following transcripts in Mouse: NM_152803, AY077467, AK154628, AK190307, AY151051, and others.

Panther Classification:

Molecular Function -

glycosidase

Gene Ontology Categories:

Process(es)

carbohydrate metabolic process
glycosaminoglycan catabolic process
proteoglycan metabolic process
cell-matrix adhesion
positive regulation of vascular endothelial growth factor production
positive regulation of blood coagulation
extracellular matrix organization
heparan sulfate proteoglycan catabolic process
positive regulation of osteoblast proliferation
regulation of hair follicle development
positive regulation of hair follicle development
positive regulation of protein kinase B signaling
angiogenesis involved in wound healing
vascular wound healing

Function(s)

beta-glucuronidase activity
protein binding
heparanase activity
heparan sulfate proteoglycan binding
syndecan binding
protein dimerization activity