HSS174647

• Gene Symbol: SPPL3
• Gene Name: signal peptide peptidase like 3
• Gene Aliases: IMP2, MDHV1887, PRO4332, PSH1, PSL4
• Chromosome Location: Chr.12: 120762510 - 120904352 on Build GRCh38
• UniGene ID: Hs.507087
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: SPPL3
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_139015.4	NP_620584.2	8, 9	1264
	XM_011537925.2	XP_011536227.1	8, 9	794
GenBank mRNA	AB252457.1	-	8, 9	856
	AJ345030.1	-	8, 9	832
	AJ420898.1	-	8, 9	803
	AK074916.1	-	7, 8	747
	AK223590.1	-	8, 9	1260
	AK291161.1	-	8, 9	1086
	AY169313.1	-	8, 9	1038
	AY358767.1	-	1, 2	110
	BC009551.1	-	1, 2	132
	BC025781.1	-	5, 6	539
	BC073910.1	-	8, 9	1045	4538522
	BC101625.1	-	8, 9	859	8069131
	BC101627.1	-	8, 9	859	8069133

More Information

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

signal peptide processing
membrane protein ectodomain proteolysis
positive regulation of cytosolic calcium ion concentration
positive regulation of protein binding
membrane protein proteolysis
positive regulation of protein dephosphorylation
T cell receptor signaling pathway
positive regulation of NFAT protein import into nucleus
positive regulation of calcineurin-NFAT signaling cascade

Function(s)

protein binding
aspartic endopeptidase activity, intramembrane cleaving
protein homodimerization activity