HSS176225

• Gene Symbol: DNMT3A
• Gene Name: DNA methyltransferase 3 alpha
• Gene Aliases: DNMT3A2, M.HsaIIIA, TBRS
• Chromosome Location: Chr.2: 25232961 - 25342590 on Build GRCh38
• UniGene ID: Hs.515840
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: DNMT3A
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001320893.1	NP_001307822.1	11	1490
	NM_022552.4	NP_072046.2	16	2176
	NM_153759.3	NP_715640.2	12	1460
	NM_175629.2	NP_783328.1	16	2247
	NR_135490.1		16	2247
	XM_005264175.4	XP_005264232.1	16	2110
	XM_005264177.4	XP_005264234.1	11	1402
	XM_011532662.2	XP_011530964.1	14	2112
	XM_011532663.2	XP_011530965.1	17	2289
	XM_011532664.2	XP_011530966.1	16	2187
	XM_011532666.2	XP_011530968.1	12	1475
	XM_011532667.2	XP_011530969.1	11	1292
	XM_017003526.1	XP_016859015.1	16	2218
	XM_017003527.1	XP_016859016.1	11	1446
GenBank mRNA	AB208833.1	-	16	2146
	AF067972.2	-	16	2138
	AF331856.1	-	16	2126
	AF480163.1	-	12	1456
	AK025230.1	-	6	500
	BC018214.1	-	1	29
	BC023612.2	-	2	228
	BC043617.1	-	16	2146	6150112

More Information

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
mitotic cell cycle
DNA methylation
methylation-dependent chromatin silencing
regulation of gene expression by genetic imprinting
spermatogenesis
aging
response to toxic substance
response to ionizing radiation
response to lead ion
DNA methylation on cytosine within a CG sequence
positive regulation of cell death
neuron differentiation
response to estradiol
response to vitamin A
response to antidepressant
response to cocaine
DNA methylation involved in embryo development
DNA methylation involved in gamete generation
hypermethylation of CpG island
negative regulation of gene expression, epigenetic
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
cellular response to amino acid stimulus
cellular response to ethanol
cellular response to hypoxia
C-5 methylation of cytosine
hepatocyte apoptotic process

Function(s)

DNA binding
chromatin binding
DNA (cytosine-5-)-methyltransferase activity
protein binding
DNA-methyltransferase activity
identical protein binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates