HSS179188

• Gene Symbol: HCK
• Gene Name: HCK proto-oncogene, Src family tyrosine kinase
• Gene Aliases: JTK9, p59Hck, p61Hck
• Chromosome Location: Chr.20: 32052188 - 32101856 on Build GRCh38
• UniGene ID: Hs.655210
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: HCK
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001172129.1	NP_001165600.1	12	1529
	NM_001172130.1	NP_001165601.1	12	1526
	NM_001172131.1	NP_001165602.1	12	1526
	NM_001172132.1	NP_001165603.1	13	1595
	NM_001172133.1	NP_001165604.1	13	1593
	NM_002110.3	NP_002101.2	12	1529
GenBank mRNA	AK026432.1	-	12	1463
	AK225819.1	-	12	1475
	AK289896.1	-	12	1517
	AK290928.1	-	13	1541
	AK298726.1	-	13	1539
	AK314335.1	-	12	1442
	BC014435.1	-	12	1415	4855747
	BC094847.1	-	12	1426	5923744
	BC108930.1	-	12	1456	40025497
	BC108931.1	-	12	1456	40025500
	BC113854.1	-	12	1453	40025503
	BC114463.1	-	12	1456	40025502
	M16592.1	-	11	1304

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013185, M83666, X62345, BC078890, S74141.

Gene Ontology Categories:

Process(es)

leukocyte migration involved in immune response
innate immune response-activating signal transduction
protein phosphorylation
inflammatory response
cell adhesion
transmembrane receptor protein tyrosine kinase signaling pathway
integrin-mediated signaling pathway
mesoderm development
positive regulation of cell proliferation
regulation of cell shape
viral process
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
cell differentiation
positive regulation of actin filament polymerization
lipopolysaccharide-mediated signaling pathway
peptidyl-tyrosine autophosphorylation
Fc-gamma receptor signaling pathway involved in phagocytosis
negative regulation of apoptotic process
leukocyte degranulation
respiratory burst after phagocytosis
protein autophosphorylation
regulation of defense response to virus by virus
regulation of inflammatory response
regulation of phagocytosis
regulation of sequence-specific DNA binding transcription factor activity
interferon-gamma-mediated signaling pathway
regulation of podosome assembly
positive regulation of actin cytoskeleton reorganization

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding