HSS186395

• Gene Symbol: TP73
• Gene Name: tumor protein p73
• Gene Aliases: P73
• Chromosome Location: Chr.1: 3652565 - 3736201 on Build GRCh38
• UniGene ID: Hs.192132
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: TP73
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001126240.2	NP_001119712.1	7	1139
	NM_001126241.2	NP_001119713.1	7	1139
	NM_001126242.2	NP_001119714.1	7	1139
	NM_001204184.1	NP_001191113.1	9	1162
	NM_001204185.1	NP_001191114.1	9	1162
	NM_001204186.1	NP_001191115.1	9	1162
	NM_001204187.1	NP_001191116.1	9	1162
	NM_001204188.1	NP_001191117.1	9	1162
	NM_001204189.1	NP_001191118.1	7	1139
	NM_001204190.1	NP_001191119.1	7	1139
	NM_001204191.1	NP_001191120.1	7	1139
	NM_001204192.1	NP_001191121.1	7	972
	NM_005427.3	NP_005418.1	9	1162
GenBank mRNA	AB055065.1	-	7	1139
	AB055066.1	-	7	1139
	AK295669.1	-	2	360
	AK302118.1	-	7	960
	AK304177.1	-	7	1108
	AK304784.1	-	7	1089
	AY040827.1	-	7	1139
	AY040828.1	-	7	1139
	AY040829.1	-	7	1139
	BC117251.1	-	9	1162	40125802
	BC117253.1	-	9	1162	40125804
	Y11416.1	-	9	1162

More Information

Panther Classification:

Molecular Function -

P53-like transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
kidney development
mismatch repair
transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
cell cycle arrest
regulation of mitotic cell cycle
intrinsic apoptotic signaling pathway in response to DNA damage
response to X-ray
response to organonitrogen compound
response to gamma radiation
regulation of gene expression
viral process
mitotic G1 DNA damage checkpoint
cellular response to UV
response to drug
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
negative regulation of JUN kinase activity
negative regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of oligodendrocyte differentiation
protein tetramerization
negative regulation of cardiac muscle cell proliferation
positive regulation of cell cycle arrest
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
p53 binding
chromatin binding
damaged DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein kinase binding
identical protein binding
transcription regulatory region DNA binding
metal ion binding