HSS188684

• Gene Symbol: GDF5
• Gene Name: growth differentiation factor 5
• Gene Aliases: BDA1C, BMP-14, BMP14, CDMP1, LAP-4, LAP4, OS5, SYM1B, SYNS2
• Chromosome Location: Chr.20: 35433347 - 35454746 on Build GRCh38
• UniGene ID: Hs.1573
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: GDF5
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_000557.4	NP_000548.2	1, 2	883
	NM_001319138.1	NP_001306067.1	3, 4	1125
	XM_011529075.2	XP_011527377.1	3, 4	1015
GenBank mRNA	AB593125.1	-	1, 2	871
	BC032495.1	-	3, 4	1125	5243109
	U13660.1	-	1, 2	883

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_003749600.
This siRNA also targets the following transcripts in Mouse: NM_008109, U08337, BC034546, AB259648.

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

chondrocyte differentiation
transforming growth factor beta receptor signaling pathway
SMAD protein import into nucleus
cell-cell signaling
positive regulation of pathway-restricted SMAD protein phosphorylation
embryonic limb morphogenesis
positive regulation of BMP signaling pathway
negative regulation of chondrocyte differentiation
positive regulation of chondrocyte differentiation
forelimb morphogenesis
hindlimb morphogenesis
growth
regulation of multicellular organism growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of neuron apoptotic process
positive regulation of neuron differentiation
cell development
negative regulation of epithelial cell proliferation
SMAD protein signal transduction
chondroblast differentiation
mitophagy in response to mitochondrial depolarization
negative regulation of mesenchymal cell apoptotic process

Function(s)

cytokine activity
transforming growth factor beta receptor binding
protein binding
growth factor activity
BMP binding
identical protein binding