HSS189606

• Gene Symbol: CFLAR
• Gene Name: CASP8 and FADD like apoptosis regulator
• Gene Aliases: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
• Chromosome Location: Chr.2: 201116015 - 201172688 on Build GRCh38
• UniGene ID: Hs.390736
• Species: Human
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: CFLAR
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_001127183.2	NP_001120655.1	3	803
	NM_001127184.2	NP_001120656.1	3	775
	NM_001202516.1	NP_001189445.1	3	775
	NM_001202517.1	NP_001189446.1	2	357
	NM_001202518.1	NP_001189447.1	1	93
	NM_001202519.1	NP_001189448.1	2	357
	NM_001308042.1	NP_001294971.1	2	447
	NM_001308043.1	NP_001294972.1	3	825
	NM_003879.5	NP_003870.4	3	775
	XM_017005189.1	XP_016860678.1	3	766
	XM_017005190.1	XP_016860679.1	3	639
	XM_017005191.1	XP_016860680.1	3	718
	XM_017005192.1	XP_016860681.1	3	766
	XM_017005193.1	XP_016860682.1	3	2783
	XM_017005194.1	XP_016860683.1	3	639
	XM_017005195.1	XP_016860684.1	4	816
	XM_017005196.1	XP_016860685.1	2	496
	XM_017005197.1	XP_016860686.1	3	2783
	XM_017005198.1	XP_016860687.1	3	639
GenBank mRNA	AB209600.1	-	3	522
	AF005774.1	-	3	745
	AF005775.1	-	2	310
	AF009616.1	-	3	722
	AF009617.1	-	2	310
	AF009618.1	-	2	310
	AF009619.1	-	2	310
	AF010127.1	-	3	720
	AF015450.1	-	3	814
	AF015451.1	-	2	310
	AF015452.1	-	2	310
	AF041458.1	-	2	325
	AF041460.1	-	2	310
	AF041461.1	-	2	265
	AF041462.1	-	1	22
	AK289913.1	-	3	599
	AK296036.1	-	2	357
	AK297387.1	-	4	672
	AK304585.1	-	1	74
	AK308767.1	-	3	685
	AK315208.1	-	3	546
	AK315924.1	-	2	161
	BC001602.1	-	3	569	3542993
	BT006751.1	-	2	310
	CD699251.1	-	1	126
	U85059.1	-	2	310
	U97074.1	-	3	692
	U97075.1	-	2	603
	Y14039.1	-	3	791
	Y14040.1	-	3	791

More Information

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
skeletal muscle tissue development
skeletal muscle atrophy
regulation of skeletal muscle satellite cell proliferation
skeletal myofibril assembly
viral process
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of I-kappaB kinase/NF-kappaB signaling
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
regulation of necroptotic process
execution phase of apoptosis
negative regulation of myoblast fusion
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protease binding
death receptor binding
protein binding
enzyme activator activity
protein complex binding
cysteine-type endopeptidase activity involved in execution phase of apoptosis