MSS207774

• Gene Symbol: Plk1
• Gene Name: polo-like kinase 1
• Gene Aliases: Plk, STPK13
• Chromosome Location: Chr.7: 122159437 - 122169875 on Build GRCm38
• UniGene ID: Mm.16525
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Plk1
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_011121.3	NP_035251.3	8	1463
GenBank mRNA	AK134045.1	-	8	1404
	AK148050.1	-	8	1377
	AK148076.1	-	8	1454
	AK164027.1	-	8	1433
	BC006880.1	-	8	1415	3596381
	L19558.1	-	8	1470
	U01063.1	-	8	1384

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_017100, BC083926, U10188.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

mitotic sister chromatid segregation
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
mitotic cytokinesis
cytokinesis
microtubule bundle formation
protein phosphorylation
cell cycle
mitotic nuclear division
mitotic spindle assembly checkpoint
regulation of mitotic cell cycle
positive regulation of peptidyl-threonine phosphorylation
phosphorylation
female meiosis chromosome segregation
protein ubiquitination
peptidyl-serine phosphorylation
regulation of mitotic metaphase/anaphase transition
G2 DNA damage checkpoint
protein destabilization
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
polar body extrusion after meiotic divisions
negative regulation of apoptotic process
regulation of protein binding
homologous chromosome segregation
establishment of protein localization
negative regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of proteolysis
centrosome organization
cell division
positive regulation of ubiquitin-protein transferase activity
synaptonemal complex disassembly
protein localization to chromatin
regulation of mitotic spindle assembly
positive regulation of ubiquitin protein ligase activity

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
microtubule binding
anaphase-promoting complex binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase binding