MSS224888

• Gene Symbol: Ercc4
• Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 4
• Gene Aliases: AI606920, Xpf
• Chromosome Location: Chr.16: 13109689 - 13152009 on Build GRCm38
• UniGene ID: Mm.287837
• Species: Mouse
• Species Specific ID (Flybase ID): -

siRNA Details

Gene Symbol: Ercc4
Interrogated Sequence		Translated Protein	Targeted Exon(s)	siRNA Location	IMAGE Clone ID
RefSeq	NM_015769.2	NP_056584.2	8, 9	2016
GenBank mRNA	AF189285.1	-	8, 9	2016
	BC026792.1	-	8, 9	1807	4911382
	CD352377.1	-	1, 2	276
	CX210668.1	-	1, 2	170

More Information

Other Species Targeted

This siRNA also targets the following transcripts in Human: NM_005236, U64315, AK289726, AK301930.

Panther Classification:

Molecular Function -

DNA metabolism protein, endodeoxyribonuclease, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

resolution of meiotic recombination intermediates
telomere maintenance
double-strand break repair via homologous recombination
DNA metabolic process
DNA repair
nucleotide-excision repair
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
cellular response to DNA damage stimulus
response to UV
UV protection
negative regulation of telomere maintenance
nucleotide-excision repair, DNA incision
cellular response to UV
nucleotide-excision repair involved in interstrand cross-link repair

Function(s)

single-stranded DNA endodeoxyribonuclease activity
TFIID-class transcription factor binding
nucleic acid binding
DNA binding
damaged DNA binding
single-stranded DNA binding
nuclease activity
endonuclease activity
endodeoxyribonuclease activity
protein binding
protein C-terminus binding
hydrolase activity
phosphoric ester hydrolase activity
structure-specific DNA binding
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
protein N-terminus binding