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Gene Symbol:
Tirap
Gene Name:
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Gene Aliases:
AA407980, C130027E04Rik, Mal, Tlr4ap, Wyatt
Chromosome Location:
Chr.9: 35184391 - 35200291 on Build GRCm38
UniGene ID:
Mm.23987
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID MSS273141
Size 20 nmol
Availability Made To Order
Catalog # 1320001
Price 459.00
Your Price
Online offer:
459.0
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Tirap
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001177845.1 NP_001171316.1 5, 6 565
NM_001177846.1 NP_001171317.1 5, 6 547
NM_001177847.1 NP_001171318.1 5, 6 493
NM_054096.2 NP_473437.2 5, 6 557
GenBank mRNA AF378130.1 - 5, 6 466
AF410784.1 - 4, 5 389
AK036431.1 - 5, 6 486
AK080135.1 - 5, 6 566
AK151117.1 - 5, 6 495
AK168494.1 - 5, 6 485
BC005584.1 - 2, 3 223 3157913
BY740695.1 - 5, 6 553
BY743490.1 - 5, 6 493

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_001055833, XM_006242794.

Gene Ontology Categories:

Function(s) Process(es)

immune system process
inflammatory response
signal transduction
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
activation of JUN kinase activity
response to bacterium
myeloid cell differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
regulation of interferon-beta production
regulation of interleukin-15 production
positive regulation of interleukin-12 production
positive regulation of interleukin-15 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor 2 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
toll-like receptor 5 signaling pathway
TIRAP-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
innate immune response
regulation of innate immune response
positive regulation of innate immune response
positive regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
interleukin-1-mediated signaling pathway
3'-UTR-mediated mRNA stabilization
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
positive regulation of neutrophil chemotaxis
positive regulation of protein homodimerization activity
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of chemokine (C-X-C motif) ligand 2 production
protein kinase C binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
Toll-like receptor 4 binding
Toll-like receptor 2 binding
protein homodimerization activity
protein heterodimerization activity

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